Santa Fe Cafe - Bluffton

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1533 Fording Island Rd Ste 302
Hilton Head Island, SC 29926

Santa Fe Café is a vibrant restaurant located on Hilton Head Island, specializing in authentic Southwestern cuisine and traditional Mexican dishes. With a visually pleasing atmosphere and a dedicated tenured staff, the eatery has been delighting both locals and visitors with its flavorful offerings for nearly 29 years.

Notable dishes include the Painted Desert Soup, Mesquite Grilled Lamb Chops, and Herb Roasted Free Range Chicken, all served in a welcoming space featuring a rooftop cantina with a romantic ambiance. The café's commitment to quality and service makes it a standout destination for those seeking a taste of the American Southwest.

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4.07 reviews
Photo of David H.
David H.
8/31/2025

This is the first time visiting the Santa Fe Cafe Bluffton location which I believe recently opened. It's in the location previously occupied by Mamma G's which closed over a year ago. The bar...

Photo of Roger M.
Roger M.
12/8/2025

Food and service was fine, food was great and we'll go back at sometime .....................................

Photo of Zayden And Lori W.
Zayden And Lori W.
9/10/2025

I really enjoyed eating at the newest Bluffton location. I had the blackened redfish. I liked all the flavor. It was to much food for just me but delicious. Service was great also. From the...

Salvatore L.
10/10/2025

We have been a fan of Santa Fe on the island for a while, so when we decided to visit the operation in Bluffton we had none of the qualms associated with going to a new restaurant. We expected...

Caroline M.
11/4/2025

Our favorite restaurant ! The food, drinks, service, and atmosphere are always wonderful. We are so happy they are in Bluffton!

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United StatesSouth CarolinaHilton Head IslandSanta Fe Cafe - Bluffton

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