Siqin Ye, MD

Visit The Center for Liver Disease and Transplantation at columbiasurgery.org/liver

Julia Wattacheril, MD, MPH is an associate professor of medicine, physician scientist, inventor and director of the Metabolic Dysfunction Associated Steatotic Liver Disease (MASLD) program at Columbia University Irving Medical Center. Her clinical and translational work spans the multidisciplinary care of MASLD patients at all stages of their disease to the investigation of rare genetic variants influencing the development and progression of MASLD before and after liver transplantation. She currently leads an interdisciplinary research group using machine learning to identify at-risk and protected phenotypes within the electronic health record (EHR) for multi-omic analysis. Of particular interest for clinical outcomes discovered through EHR phenotyping include rapid progression to advanced liver disease, need for transplantation and hepatocellular carcinoma. Awards include the Department of Surgery Innovation Award and Columbia Department of Biomedical Engineering Ignition Award for these software applications as they move into medicine. Wattacheril is the lead principal investigator for several clinical trials in MASH. Her early pilot work with proteomics and lipidomics in the development of metabolic dysfunction associated steatohepatitis (MASH) led to her current efforts investigating multi-omic signatures associated with fibrotic MASH. She co-led a multicenter consortium investigating the clinical risks associated with the development of hepatocellular carcinoma in patients with all etiologies of chronic liver disease, with a particular local focus on diverse populations. At Columbia, she works closely with the Center for Precision Medicine and Genomics to integrate genomics into clinical care. She mentors across disciplines including computational geneticists to masters’ program students in nutrition to undergraduates in psychology. She has a commitment to community education, including faith-based and non-profit sectors.

If you need assistance in Chinese (Mandarin & Cantonese), please call 646-317-6325. Visit Columbia Liver Asian Outreach Office (English | Mandarin) Dr. Rajani Sharma earned her AB at Princeton University prior to attending Rutgers University-Robert Wood Johnson Medical School. She completed her residency in Internal Medicine at New York Presbyterian Hospital-Columbia University Irving Medical Center, where she received a resident teaching award. She then completed her gastroenterology fellowship and transplant hepatology fellowship also at New York Presbyterian Hospital-Columbia University Irving Medical Center. During her gastroenterology fellowship, she earned a Masters in Patient Oriented Research at the Mailman School of Public Health. Dr. Sharma strives to provide empathetic and thoughtful care that focuses on the specific needs of each of her patients. Her clinical practice is focused on the management of all types of liver disease. In addition, Dr. Sharma has specialized training in managing complications of end-stage liver disease and caring for patients before and after liver transplantation. Visit The Center for Liver Disease and Transplantation at columbiasurgery.org/liver