SemaThera Inc

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Westmount, QC

SemaThera Inc, based in Westmount, Quebec, is dedicated to developing innovative treatments for diabetic and other retinal degenerative diseases. With over a decade of research led by Professor Przemyslaw Mike Sapieha, the company focuses on the role of semaphorins, particularly semaphorin 3A, in the progression of diabetic retinopathy and diabetic macular edema.

The company has created a family of biological traps designed to bind and sequester semaphorin 3A and other cytokines associated with diabetic retinopathy. These traps have demonstrated the ability to reduce retinal vascular leakage, inflammation, and promote physiological revascularization in various models of retinal vascular diseases.

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